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«Cocaine»
CSA Names: Cocaine
CSA Location: Schedule II Section (b) Subsection (4)
CSA History: Scheduled in Public Law 91-513, the original CSA of 1970
Names: Methyl (3S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate (IUPAC ACD/Name)
Molecular formula: C17H21NO4
Nominal mass: 303
Average mass: 303.3529
Monoisotopic mass: 303.147058
CAS registry number: 50-36-2
ChemSpider: 4475153
PubChem: 5760
Wikipedia: Cocaine
Erowid: Cocaine
Drugs-Forum: Cocaine
Bluelight: Cocaine
Standard InChI: InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12?,13?,14-,15+/m0/s1
Standard InChIKey: ZPUCINDJVBIVPJ-PFSRBDOWSA-N
SMILES: COC(=O)[C@H]1[C@H](CC2N(C1CC2)C)OC(=O)c1ccccc1
Tags: USCSA
 
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cocaine base.pdf ATR IR Thermo Nicolet
cocaine hcl.pdf ATR IR Thermo Nicolet
cocaine TDTA.pdf ATR IR Cocaine-TDTA derivative / Thermo Nicolet
cocaine.pdf EI MS Agilent MSD
Cocaine base.bmp GC IRD Used with Permission of Oklahoma State Bureau of Investigation, Forensic Science Center, Controlled Substances Laboratory.
Cocaine HCL.bmp GC IRD Used with Permission of Oklahoma State Bureau of Investigation, Forensic Science Center, Controlled Substances Laboratory.
cocaine-IR.jdx IR NIST Standard Reference Data Program Collection (C) 2009 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved.
cocaine-Mass.jdx MS NIST Mass Spectrometry Data Center Collection (C) 2008 copyright by the U.S. Secretary of Commerce on behalf of the United States of America. All rights reserved.
cocaine base-raman.pdf RAMAN GBI DOFS
cocaine HCl-raman.pdf RAMAN GBI-DOFS
Cocaine edit.pdf SP-GC-IR DiscovIR
Vendor ID URL
Cerilliant C-008 http://www.cerilliant.com/shoponline/Item_Details.aspx?itemno=a8fffeab-5377-4e07-8eda-40fe976722d1
Grace Davison (Alltech) 01800 http://www.discoverysciences.com/uploadedFiles/Library/Technical_Literature/Brochures/B505A_Drug_Catalog_LR_04_17_09.pdf
LGC LGCAMP1345.05-12 http://www.lgcstandards.com/epages/LGC.sf/en_GB/?ObjectPath=/Shops/LGC/Products/LGCAMP1345.05-11
Lipomed COC-156-HC http://www.lipomed.com/index.php?eid=138§ion=mediadir&cmd=detail
Lipomed COC-156-FB http://www.lipomed.com/index.php?eid=32§ion=mediadir&cmd=detail
Sigma Aldrich C5776-1G http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=C5776|SIGMA&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC
Sigma Aldrich C8912 http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=C8912|SIGMA&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC
Sigma Aldrich 51621 http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=51621|FLUKA&N5=SEARCH_CONCAT_PNO|BRAND_KEY&F=SPEC
Spectrum C2772 https://www.spectrumchemical.com/OA_HTML/chemical-products_Cocaine-Free-Base-CII_C2772.jsp?minisite=10020&respid=22372
Spectrum C1408 https://www.spectrumchemical.com/OA_HTML/chemical-products_Cocaine-Hydrochloride-CII-USP_C1408.jsp?minisite=10020&respid=22372
Tocris Bioscience 2833 http://www.tocris.com/dispprod.php?ItemId=5327&Controlled
Toronto Research Chemicals C633500 http://www.trc-canada.com/detail.php?CatNum=C633500
U.S. Pharmacopeia 1143008 http://store.usp.org/OA_HTML/ibeCCtpItmDspRte.jsp?a=b&item=18649
Title Publication Date Vol. Iss. Page(s) Remarks
The Qualitative Determination of Trace Amounts of Cocaine Obtained Through Casual Contact Microgram Bulletin 1994-06-00 Vol 27 (6) Maloney et al.
A Discussion of “Cocaine Base” and “Cocaine” - The Case Law Concerning the Sufficiency of the Definition of Cocaine Base... Journal of CLIC 1992-01-00 Vol 2 (1) Law Enforcement Restricted
N-ACETYLNORCOCAINE: A NEW COCAINE IMPURITY FROM CLANDESTINE PROCESSING. I. Journal of CLIC 1991-10-00 Vol 1 (4) Law Enforcement Restricted
Four New Illicit Cocaine Impurities from the Oxidation of Crude Cocaine Base: Formation and Characterization... Journal of Forensic Sciences 2007-07-00 Vol 52 (4) John F. Casale B.S. et al
Tropane Ethyl Esters in Illicit Cocaine: Isolation, Detection, and Determination of New Manufacturing By-Products from the Clandestine Purification of Crude Cocaine Base with Ethanol Journal of Forensic Sciences 2008-05-00 Vol 53 (3) John F. Casale B.S. et al
Cocaine in Bleach: Destroying the Evidence Identification of Degradation Products Microgram Bulletin 1994-08-00 Vol 27 (8) Carpenter and Laing
Microcrystal Analysis of Cocaine Hydrochloride and Added Adulterants Journal of Forensic Sciences 2011-05-00 Vol 56 (3) Hannah C. Nelson B.S. et al
N-Acetylbenzocaine: Formation via Transacetylation of Benzocaine and Acetylsalicylic Acid in a Cocaine Exhibit Microgram Journal 2010-03-00 Vol 7 (1) John F. Casale, Minh C. Nguyen
The Mass Spectrum of Cocaine:Deuterium Labeling and MS/MS Studies Microgram Journal 2010-03-00 Vol 7 (1) R. Martin Smith and John F. Casale
Identification of Levamisole Impurities Found in Illicit Cocaine Exhibits Microgram Journal 2008-07-00 Vol 6 (3-4) John F. Casale, Elizabeth M. Corbeil, and Patrick A. Hays
An In-Depth Study of the Peruvian Base Llavada (“Washed Base”) Technique for Purification of Crude Cocaine Base Microgram Journal 2008-07-00 Vol 6 (3-4) Danielle K. Boudreau, John F. Casale
Identification of Diltiazem Impurities / Artifacts during the Analyses of Illicit Cocaine Exhibits Containing Diltiazem Microgram Journal 2008-07-00 Vol 6 (3-4) John F. Casale, Pauline M. Orlando, Valerie L. Colley, and Patrick A. Hays
Determination of Cocaine in Various South American Commercial Coca Products Microgram Journal 2008-07-00 Vol 6 (3-4) Elizabeth M. Corbeil and John F. Casale
“Crack” Cocaine: A Study of Stability over Time and Temperature Microgram Journal 2008-07-00 Vol 6 (3-4) Laura M. Jones, Danielle K. Boudreau, and John F. Casale
The Discoloration of Illicit Drug Samples [cocaine exhibits] Microgram Journal 2008-07-00 Vol 6 (3-4) James M. Moore and John F. Casale
Discovery of an Interesting Temperature Effect on the Sensitivity of the Cobalt Thiocyanate Test for Cocaine Microgram Journal 2009-01-00 Vol 6 (1-2) Jim W. McGill, Crystal A. Dixon, and David Ritter
Comparison of the Novel Direct Analysis in Real Time Time-of-Flight Mass Spectrometry (AccuTOF-DART™) and Signature Analysis for theIdentification of Constituents of Refined Illicit Cocaine Microgram Journal 2007-12-00 Vol 5 (1-4) Jeri D. Ropero-Miller, Peter R. Stout, Nichole D. Bynum and John F. Casale
Isolation of cis-Cinnamoylcocaine from Crude Illicit Cocaine via Alumina Column Chromatography Microgram Journal 2006-12-00 Vol 4 (1-4) John F. Casale, Enrique L. Piñero, and Elizabeth M. Corbeil
Quantitation of Cocaine by Gas Chromatography-Flame Ionization Detection Utilizing Isopropylcocaine as a Structurally Related Internal Standard Microgram Journal 2006-12-00 Vol 4 (1-4) Enrique L. Piñero and John F. Casale
Assessment of the Volatility (Smokeability) of Cocaine Base Containing 50 Percent Mannitol: Is it a Smokeable Form of “Crack” Cocaine? Microgram Journal 2005-12-00 Vol 3 (3-4) John F. Casale
Levamisole: An Analytical Profile Microgram Journal 2005-12-00 Vol 3 (3-4) Ann Marie M. Valentino and Ken Fuentecilla
A Study of Acids Used for the Acidified Cobalt Thiocyanate Test for Cocaine Base Microgram Journal 2003-06-00 Vol 1 (1-2) Anna L. Deakin
Selected Intelligence Brief Cocaine Signature Program Report (January 2003) Microgram Bulletin 2003-02-00 Vol 36 (2)
Analysis of Cocaine HCl in Wax (Law enforcement restricted publication) Microgram Bulletin 2001-07-00 Vol 34 (7) Ruurd Jellema
Levels of Residual Cocaine Base Found in Smoking Devices in Central Florida (Law enforcement restricted publication) Microgram Bulletin 2001-12-00 Vol 34 (12) Frank T. Davis and Kevin L. Bass
On the Use of Activated Charcoal to Circumvent Canine Detection of Concealed Narcotics-Part I (Law enforcement restricted publication) Microgram Bulletin 2000-04-00 Vol 33 (4) D-T Vu
Effects of Cyanoacrylate Processing on Cocaine HCl Trace Analysis (Law enforecement restricted publication) Microgram Bulletin 2000-05-00 Vol 33 (5) Thomas A. Morris and Andrew S. Michiels
THE USE OF SPECIFIC INFRARED ABSORPTION BANDS TO DISTINGUISH COCAINE BASE AND COCAINE HCL WHEN MIXED WITH KNOWN ADULTERANTS OR DILUENTS (Law enforcement restricted publication) Microgram Bulletin 2000-09-00 Vol 33 (9) Raul Morales
QUANTITATION OF ILLICIT DRUGS IN ROUTINE FORENSIC ANALYSIS VIA NMR (Law enforcement restricted publication) Microgram Bulletin 1999-11-00 Vol 32 (11) Clay P. Phelan
Solubility of Cocaine Free Base and Cocaine Hydrochloride in Gasoline (Law enforcement restricted publication) Microgram Bulletin 1998-02-00 Vol 31 (2) Jerry F. O'Donnell and John D. Paulson
Determination of Cocaine in Suspected Narcotic Substances by FTIR and HPTLC Methods (Law Enforcement Restricted Publication) Microgram Bulletin 1996-03-00 Vol 29 (3) Utpal Saha, et al.
THE STABILITY OF COCAINE IN AGUA RICA/AGUA MADRE (Law Enforcement Restricted Publication) Microgram Bulletin 1996-07-00 Vol 29 (7) John F. Casale and Richard P. Meyers
IDENTIFICATION OF DIMETHYL TEREPHTHALATE IN COCAINE SAMPLES (Law Enforcement Restricted Publication) Microgram Bulletin 1996-12-00 Vol 29 (12) Charles E. Matkovich
Passive Contamination of Undercover Narcotics Officers by Cocaine: An Assessment of Their Exposure Using Hair Analysis (Law Enforcement Restricted Publication) Microgram Bulletin 1995-06-00 Vol 28 (6) Tom Mieczkowski
Evaluation of the composition of street cocaine seized in two regions of Brazil Sci. and Justice J. 2013-12-01 Vol 53 (425-432) Elisângela Jaqueline Magalhães et al
Analysis of cocaine and its adulterants in drugs for international trafficking seized by the Brazilian Federal Police For. Sci. Int. 2015-02-01 Vol 247 (48-53) Silvio Fernandes Lapachinske et al
Headspace-Gas Chromatographic-Mass Spectrometric Analysis of South American Commercial Solvents and their Use in the Illicit Conversion of Cocaine Base to Cocaine Hydrochloride J. For. Sci. 2015-01-01 Vol 60 (45-53) Jennifer R. Mallette and John F. Casale
Identification of Different Forms of Cocaine and Substances Used in Adulteration Using Near-infrared Raman Spectroscopy and Infrared Absorption Spectroscopy Brazil J. For. Sci. 2015-01-01 Vol 60 (171-178) Ciro A. F. O. Penido et al
DETECTION AND QUANTITATION OF COCAINE AND METABOLITES IN URINE AND HAIR AFTER CONSUMPTION OF COCA TEA Problems of Forensic Sciences 2013-00-00 Vol XCIII Teresa GRAY1, Larry BRACE2, Steve SHAH2, Thomas TOLHURST1, Matthew JUHASCIK1, Adam NEGRUSZ1
The Cocaine Diastereoisomers. DOI: 10.1520/JFS11325J Journal of Forensic Sciences 1981-01-01 Vol 26 (1) A. C. Allen, D. A. Cooper, W. O. Kiser, R. C. Cottrell
HPLC analysis of cocaine diastereoisomers by chiral stationary phase. DOI: 10.1016/0379-0738(90)90164-T For. Sci. Int. 1990-01-01 Vol 44 M. Chiarotti, N. Fucci
Recent advances in forensic drug analysis by DART-MS. DOI: 10.4155/bio.14.31 Bioanalysis 2014-03-01 Vol 6(6) Ashton D Lesiak & Jason RE Shepard
Separation of optical isomers of scopolamine, cocaine, homatropine, and atropine. DOI:10.1016/0003-2697(87)90161-8 Analytical Biochemistry 1987-12-01 Vol 167 (2) Daniel W. Armstrong, Soon M. Han, Yoon I. Han
A forensic case study: the detection of contraband drugs in carrier solutions by Raman spectroscopy Drug Testing and Analysis 2011-09-01 Vol 3 (9) A. D. Burnett, H. G. M. Edwards, M. D. Hargreaves, T. Munshi, and K. Page
Profiling cocaine by ATR–FTIR For. Sci. Int. 2015-01-01 Vol 246 M.C.A. Marcelo, K.C. Mariotti, M.F. Ferrão, R.S. Ortiz
A green method for the determination of cocaine in illicit samples For. Sci. Int. 2014-04-01 Vol 237 Clara Pérez-Alfonso, Nieves Galipienso, Salvador Garrigues, Miguel de la Guardia
The evaluation of evidence relating to traces of cocaine on banknotes For. Sci. Int. 2014-03-01 Vol 236 Amy Wilson, Colin Aitken, Richard Sleeman, James Carter
Development and validation of an HPLC-DAD method for simultaneous determination of cocaine, benzoic acid, benzoylecgonine and the main adulterants found in products For. Sci. Int. 2014-02-01 Vol 235 Gisele Floriani, João Cleverson Gasparetto, Roberto Pontarolo, Alan Guilherme Gonçalves
Use of NMR in profiling of cocaine seizures For. Sci. Int. 2013-09-10 Vol 231 Bruno Pagano
Analysis of illicit cocaine and heroin samples seized in Luxembourg from 2005–2010 For. Sci. Int. 2011-11-10 Vol 212 Serge Schneider, François Meys
Screening for illicit drugs on Euro banknotes by LC–MS/MS For. Sci. Int. 2011-03-20 Vol 206 Kurt Wimmer, Serge Schneider
Reliability of ion mobility spectrometry for qualitative analysis of complex, multicomponent illicit drug samples For. Sci. Int. 2011-03-20 Vol 206 Jennifer R. Verkouteren, Jessica L. Staymates
Voltammetric determination of cocaine in confiscated samples using a cobalt hexacyanoferrate film-modified electrode For. Sci. Int. 2009-11-20 Vol 192 Érica Naomi Oiye et al
Validation of an ion mobility spectrometry (IMS) method for the detection of heroin and cocaine on incriminated material For. Sci. Int. 2008-05-20 Vol 177 Franz E. Dussy et al
Cocaine profiling for strategic intelligence, a cross-border project between France and Switzerland Part II. Validation of the statistical methodology for the profiling of cocaine For. Sci. Int. 2008-05-20 Vol 177 S. Lociciro, P. Esseiva, P. Hayoz, L. Dujourdy, F. Besacier, P. Margot
Evidence on unusual way of cocaine smuggling: Cocaine-polymethyl methacrylate (PMMA) solid solution—study of clandestine laboratory samples For. Sci. Int. 2007-07-04 Vol 169 T. Gostič, S. Klemenc
"Cocaine profiling for strategic intelligence purposes, a cross-border project between France and Switzerland For. Sci. Int. 2007-04-11 Vol 167 S. Lociciro et al
Development of a capillary zone electrophoresis method including a factorial design and simplex optimisation for analysis of amphetamine, amphetamine analogues, cocaine, and heroin For. Sci. Int. 2006-03-10 Vol 157 Johan Dahlén, Sylvia von Eckardstein
Adulterants encountered in the illicit cocaine market For. Sci. Int. 1998-08-12 Vol 95 Nadia Fucci, Nadia De Giovanni
Capillary electrophoresis of illicit drug seizures For. Sci. Int. 1998-04-05 Vol 92 Ira S Lurie
Purity of cocaine seized in Spain, 1985–1993: variations by weight, province and year of seizure For. Sci. Int. 1997-02-07 Vol 83 Gregorio Barrio et al
A database for comparison analysis of illicit cocaine samples For. Sci. Int. 1994-11-14 Vol 69 Kathrine E. Janzen, Angelo R. Fernando, Leo Walter
Nuclear magnetic resonance identification and estimation of solvent residues in cocaine For. Sci. Int. 1991-03-01 Vol 49 Hajro W. Avdovich, Michael J. Lebelle, Céline Savard, W.L. Wilson
Detection of pseudoecgonine and differentiation from ecgonine in illicit cocaine For. Sci. Int. 1990-10-01 Vol 47 John F. Casale
A facile procedure for the synthesis of pseudococaine from cocaine For. Sci. Int. 1989-09-01 Vol 43 Wing-Wah Sy, Bruce A. Lodge
A practical total synthesis of cocaine's enantiomers For. Sci. Int. 1987-01-01 Vol 33 John F. Casale
A quantitative densitometric determination of heroin and cocaine samples by high-performance thin-layer chromatography For. Sci. Int. 1986-10-01 Vol 32 E. Della Casa, G. Martone
An improved method for the rapid screening of illicit cocaine preparations using high performance liquid chromatography with electrochemical detection For. Sci. Int. 1986-07-14 Vol 31 Carl M. Selavka, Ira S. Krull, Ira S. Lurie
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Microcrystal Analysis of Cocaine Hydrochloride and Added Adulterants J. For. Sci. 2011-05-01 Vol 56 Hannah C. Nelson, Elizabeth A. Gardner and Dan Matteo
Tropane Ethyl Esters in Illicit Cocaine: Isolation, Detection, and Determination of New Manufacturing By-Products from the Clandestine Purification of Crude Cocaine Base with Ethanol J. For. Sci. 2008-05-01 Vol 53 John F. Casale, Danielle K. Boudreau and Laura M. Jones
Four New Illicit Cocaine Impurities from the Oxidation of Crude Cocaine Base: J. For. Sci. 2007-07-01 Vol 52 John F. Casale et al
Evaluation of Solid-Phase Microextraction Desorption Parameters for Fast GC Analysis of Cocaine in Coca Leaves J. Chrom. Sci. 2006-08-01 Vol 44 (7) Yara Ilias, Stefan Bieri, Philippe Christen and Jean-Luc Veuthey
Rapid Gas Chromatographic Analysis of Drugs of Forensic Interest J. Chrom. Sci. 1999-06-01 Vol 37 (6) Tricia A. Williams, Michelle Riddle, Stephen L. Morgan, and William E. Brewer
Chemosystematic identification of fifteen new cocaine-bearing Erythroxylum cultigens grown in Colombia for illicit cocaine production For. Sci. Int. 2014-04-01 Vol 237 John F. Casale, Jennifer R. Mallette, Laura M. Jones
Analysis of Currency for Cocaine Contamination Canadian For. Sci. 1989-01-01 Vol 22 (203-218) J.C. Hudson
Trace Analysis of Cocaine and Heroin in Different Customs Scenarios using a Custom-Built Ion Mobility Spectrometer Canadian For. Sci. 1991-01-01 Vol 24 (43-49) Mohinder Chauhan et al
Cocaine Analysis in Hair: Solid-Phase Microextraction (SPME) Versus Supercritical Fluid Extraction (SFE) Canadian For. Sci. 2001-01-01 Vol 40 (143-149) S. Schiavone et al
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